INJE PharmacoGenomics Research Center

· Parvez MM, Kaisar N, Shin HJ, Lee YJ, Shin JG

Comprehensive substrate characterization of 22 antituberculosis drugs for multiple solute carrier (SLC) uptake transporters, in vitro (cPMTb)

Antimicrob Agents Chemother. 27;62(9):e00512-18 / 2018.08 [LINK]

· Jeong ES, Kim GB, Yim DE, Moon KS, Lee SJ, Shin JG, Kim DH

Identification and characterization of amiodarone metabolites in rats using UPLC-ESI-QTOFMS-based untargeted metabolomics approach (cPMTb)

J Toxicol Environ Health A. 81(12):481-492 / 2018.05 [LINK]

· Oh MK, Ghim JL, Park SE, Kim EY, Shin JG

Pharmacokinetic comparison of a fixed-dose combination versus concomitant administration of fimasartan, amlodipine, and rosuvastatin using partial replicated design in healthy adult subjects (cPMTb)

Drug Des Devel Ther. 8:12:1157-1164 / 2018.05 [LINK]

· Bergmeijer TO, ~, Shin JG, ~ Shuldiner AR; ICPC Investigators.

Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical endpoints - Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC) (cPMTb)

Am Heart J. 198:152-159 / 2018.04 [LINK]

· Kim WY, Lee SJ, Min JK, Oh KS, Kim DH, Kim HS, Shin JG.

Identification of novel CYP4F2 genetic variants exhibiting decreased catalytic activity in the conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) (cPMTb)

Prostaglandins Leukot Essent Fatty Acids. 131:6-13 / 2018.04 [LINK]

· Kim HS, Chang K, Koh YS, Park MW, Choi YS, Park CS, Oh M, Kim EY, Shon JH, Shin JG, Seung KB.

CYP2C19 poor metabolizer is associated with clinical outcome of clopidogrel therapy in acute myocardial infarction but not stable angina. (BMRC, PRCDM)

Circ Cardiovasc Genet. 6(5):514-21 / 2013.10 [LINK]

2013-International

· Jarrar YB, Cho SA, Oh KS, Kim DH, Shin JG, Lee SJ.

Identification of cytochrome P450s involved in the metabolism of arachidonic acid in human platelets. (BMRC, PRCDM)

Prostaglandins Leukot Essent Fatty Acids. 89(4):227-34 / 2013.09 [LINK]

2013-International

· Park MW, Her SH, Kim HS, Choi YS, Park CS, Koh YS, Park HJ, Kim PJ, Kim CJ, Jeon DS, Shin DI, Seo SM, Yoo KD, Kim DB, Kim HY, Lee JM, Chung WS, Seung KB, Shin JG, Chang K.

Impact of the CYP2C19*17 polymorphism on the clinical outcome of clopidogrel therapy in Asian patients undergoing percutaneous coronary intervention. (PRCDM)

Pharmacogenet Genomics. 23(10):558-62 / 2013.10 [LINK]

2013-International

· Lee SJ, Kim WY, Jarrar YB, Kim YW, Lee SS, Shin JG.

Single nucleotide polymorphisms in SULT1A1 and SULT1A2 in a Korean population. (BMRC, PRCDM)

Drug Metab Pharmacokinet. 28(4):372-7 / 2013.05 [LINK]

2013-International

· Kim HJ, Jeong ES, Seo KA, Shin KJ, Choi YJ, Lee SJ, Ghim JL, Sohn DR, Shin JG, Kim DH.

Glucuronidation of a sarpogrelate active metabolite is mediated by UDP-glucuronosyltransferases 1A4, 1A9, and 2B4. (BMRC)

Drug Metab Dispos. 41(8):1529-37 / 2013.08 [LINK]

2013-International

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